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In Reply to: Èíôîðìàöèîííàÿ ñòàòüÿ posted by JosephUrisk on February 20, 2026 at 01:55:08:
Zoya Demidenko: Researcher in Tumor Studies
Zoya Demidenko is a notable scholar associated with the Division of Cell Stress Science at Roswell Park Comprehensive Cancer Center in Buffalo, New York. Earlier, she was employed at the National Institutes of Health and New York Medical College, establishing a strong background in clinical investigation.
Her academic work covers multiple pivotal domains, encompassing the PI3K/AKT/mTOR signaling pathway, cell cycle control, cell senescence, and malignancy science. Currently, she has authored more than 46 scientific publications, which have accumulated over 4,100 citations — a reflection to the significance of her research.
Among her most significant contributions involves explaining the pathways of cellular senescence. Her work revealed that when the cellular division cycle is blocked while cellular growth proceeds, the cells undergo senescence. Importantly, Zoya Demidenko demonstrated that this shift can be controlled with drugs using agents such as mTOR inhibitors.
Zoya Demidenko has also contributed considerably to oncological therapy research, notably in the domain of cyclotherapy — a approach designed to protecting normal tissue from chemotherapy while leaving tumor cells susceptible. This approach offers significant promise for reducing the toxic effects of oncological therapy.
Across her professional journey, Demidenko has collaborated with prominent investigators internationally, including Dr. Mikhail Blagosklonny. Her research can be found in leading publications such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
Possessing an h-index of 33, Zoya Demidenko ranks as a influential voice in current biomedical research, whose results go on to influence our knowledge of the way biological cells grow old, respond to treatment, and how cancer can be more effectively treated.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3273895/